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Query: FLNB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FLNB 0 2.452 0.270 -0.330 0.666 -0.358 0.161 0.052

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FLNB Phosphorylation S2478 1.402 1.309 _LVS(ph)PGSANETSSILVESVTR_
FLNB Phosphorylation S2107 0.761 _APS(ph)VATVGSICDLNLK_
FLNB Phosphorylation S983 0.095 _LDVTILS(ph)PSR_
FLNB Ubiquitylation K1897 -0.998 _YNDK(gl)HIPGSPFTAK_
FLNB Ubiquitylation K1955 -0.780 _DEPCLLK(gl)R_

Background Information for FLNB:


Pubmed-FLNB »
Uniprot-FLNB »
Biogrid-FLNB »
ProteomicsDB-FLNB »

Tumorportal-FLNB »
COSMIC-FLNB »
GenomeRNAi-FLNB »
Genecards-FLNB


Protein-protein Interactions for FLNB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait RALA Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FLNB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CH-domain IPR001715 0.63
Category members Filamin/ABP280_rpt IPR001298 0.02
Category members Filamin/ABP280_repeat-like IPR017868 0
Category members Ig_E-set IPR014756 0


Protein complexes (CORUM database) featuring FLNB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FLNB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0007016 cytoskeletal anchoring at plasma membrane Database 0.74
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0030018 Z disc Database 0.32
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Disease phenotype Atelosteogenesis_type_II Atelosteogenesis type II Database 0.15
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007519 skeletal muscle tissue development Database 0


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