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Query: FLII

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FLII 0 1.250 1.420 -1.130 0.242 0.022

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FLII Ubiquitylation K30 0.168 _GGYFPENVK(gl)AMTSLR_
FLII Phosphorylation S856 -0.050 -0.073 _NAEAVLQS(ph)PGLSGK_
FLII Ubiquitylation K290 -0.825 _NQLTSLPSAICK(gl)LSK_
FLII Ubiquitylation K834 -1.474 -0.885 _SLEGTEAQVFKAK(gl)_
FLII Ubiquitylation K862 -0.951 _NAEAVLQSPGLSGK(gl)VK_
FLII Ubiquitylation K864 -0.809 -0.951 _NAEAVLQSPGLSGKVK(gl)_
FLII Ubiquitylation K671 -0.997 _GAQATLSSTTK(gl)AR_
FLII Ubiquitylation K832 -1.241 _SLEGTEAQVFK(gl)AK_
FLII Ubiquitylation K752 -0.493 _LSVEHK(gl)QRPK_
FLII Ubiquitylation K756 -0.838 _LSVEHKQRPK(gl)_
FLII Ubiquitylation K1035 0.941 _FLSHFK(gl)R_

Background Information for FLII:


Pubmed-FLII »
Uniprot-FLII »
Biogrid-FLII »
ProteomicsDB-FLII »

Tumorportal-FLII »
COSMIC-FLII »
GenomeRNAi-FLII »
Genecards-FLII


Protein-protein Interactions for FLII
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLII Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1430 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRRFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAT9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FLII
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32
Category members Gelsolin-like_dom IPR007123 0.09
Category members Villin/Gelsolin IPR007122 0


Protein complexes (CORUM database) featuring FLII
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FLII
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members Disease phenotype SMITH-MAGENIS_SYNDROME SMITH-MAGENIS SYNDROME Database 0.09
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006936 muscle contraction Database 0


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