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Query: FEM1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FEM1B 0 1.520 0.160 -0.170 -0.164 0.702

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FEM1B Ubiquitylation K594 0.378 0.605 _TQMK(gl)MSLK_
FEM1B Ubiquitylation K598 -0.824 -0.169 _MSLK(gl)CLAAR_

Background Information for FEM1B:


Pubmed-FEM1B »
Uniprot-FEM1B »
Biogrid-FEM1B »
ProteomicsDB-FEM1B »

Tumorportal-FEM1B »
COSMIC-FEM1B »
GenomeRNAi-FEM1B »
Genecards-FEM1B


Protein-protein Interactions for FEM1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait ALDH1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSPRY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNTF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CUL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM125B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXRED2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLMN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SHKBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOMM22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FEM1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring FEM1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FEM1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0002070 epithelial cell maturation Database 0
Category members GO Category GO:0005123 death receptor binding Database 0
Category members GO Category GO:0051438 regulation of ubiquitin-protein ligase activity Database 0
Category members GO Category GO:0060442 branching involved in prostate gland morphogenesis Database 0
Category members GO Category GO:0060743 epithelial cell maturation involved in prostate gland development Database 0


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