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Query: FAM46C

This is a cancer-associated gene according to the Broad and Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FAM46C 0 0.574 0.480 -0.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FAM46C Ubiquitylation K128 0.574 _LK(gl)ISPVTLK_

Background Information for FAM46C:


Pubmed-FAM46C »
Uniprot-FAM46C »
Biogrid-FAM46C »
ProteomicsDB-FAM46C »

Tumorportal-FAM46C »
COSMIC-FAM46C »
GenomeRNAi-FAM46C »
Genecards-FAM46C


Protein-protein Interactions for FAM46C
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in FAM46C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DUF1693 IPR012937 0


Protein complexes (CORUM database) featuring FAM46C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FAM46C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14


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