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Query: FADS3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FADS3 0 -0.119 1.380 -0.330

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FADS3 Ubiquitylation K405 -0.119 _VAPLVK(gl)SLCAK_

Background Information for FADS3:


Pubmed-FADS3 »
Uniprot-FADS3 »
Biogrid-FADS3 »
ProteomicsDB-FADS3 »

Tumorportal-FADS3 »
COSMIC-FADS3 »
GenomeRNAi-FADS3 »
Genecards-FADS3


Protein-protein Interactions for FADS3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FADS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FADS3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyt_B5-like_heme/steroid-bd IPR001199 1.28
Category members Fatty_acid/sphinglp_desaturase IPR012171 0.17
Category members Fatty_acid_desaturase-1 IPR005804 0


Protein complexes (CORUM database) featuring FADS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FADS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0006636 unsaturated fatty acid biosynthetic process Database 0.07
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0020037 heme binding Database 0.04
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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