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Query: FADS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FADS2 0 0.932 0.940 -0.140 -0.281 0.284

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FADS2 Ubiquitylation K42 0.732 _K(gl)VYNITK_
FADS2 Ubiquitylation K108 0.196 0.446 _NSK(gl)ITEDFR_
FADS2 Ubiquitylation K404 -1.180 -0.072 _IAPLVK(gl)SLCAK_
FADS2 Ubiquitylation K417 -0.712 _HGIEYQEK(gl)PLLR_
FADS2 Ubiquitylation K409 -1.496 -0.749 _SLCAK(gl)HGIEYQEKPLLR_

Background Information for FADS2:


Pubmed-FADS2 »
Uniprot-FADS2 »
Biogrid-FADS2 »
ProteomicsDB-FADS2 »

Tumorportal-FADS2 »
COSMIC-FADS2 »
GenomeRNAi-FADS2 »
Genecards-FADS2


Protein-protein Interactions for FADS2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in FADS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyt_B5-like_heme/steroid-bd IPR001199 1.28
Category members Fatty_acid/sphinglp_desaturase IPR012171 0.17
Category members Fatty_acid_desaturase-1 IPR005804 0


Protein complexes (CORUM database) featuring FADS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FADS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_144 KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS 0 0.13
Category members Pathway Pathway_143 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM 0 0.07
Category members GO Category GO:0033559 unsaturated fatty acid metabolic process Database 0.07
Category members GO Category GO:0036109 alpha-linolenic acid metabolic process Database 0.07
Category members GO Category GO:0006636 unsaturated fatty acid biosynthetic process Database 0.07
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0020037 heme binding Database 0.04
Category members Pathway Pathway_151 KEGG_ALPHA_LINOLENIC_ACID_METABOLISM 0 0.03
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0004768 stearoyl-CoA 9-desaturase activity Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Database 0
Category members GO Category GO:0043651 linoleic acid metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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