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Query: ETFA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ETFA 0 0.414 0.340 -0.390 0.231 1.141 -3.119 0.745 0.642

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ETFA Ubiquitylation K226 0.836 -0.062 _GLK(gl)SGENFK_
ETFA Ubiquitylation K206 -1.212 _LTK(gl)SDRPELTGAK_

Background Information for ETFA:





Protein-protein Interactions for ETFA

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EXOSC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SMS Cat. description Hein, Mann, Cell 2015
Category members IP bait TGS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LYRM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ETFA

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ETF_a/b_N IPR014730 0
Category members DHS-like_NAD/FAD-binding_dom IPR029035 0


Protein complexes (CORUM database) featuring ETFA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ETFA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Disease phenotype MULTIPLE_ACYL-CoA_DEHYDROGENASE_DEFICIENCY MULTIPLE ACYL-CoA DEHYDROGENASE DEFICIENCY Database 0.01
Category members Disease phenotype Multiple_acyl-CoA_dehydrogenation_deficiency_mild_type Multiple acyl-CoA dehydrogenation deficiency mild type Database 0.01
Category members Disease phenotype Multiple_acyl-CoA_dehydrogenation_deficiency_severe_neonatal_type Multiple acyl-CoA dehydrogenation deficiency severe neonatal type Database 0.01
Category members GO Category GO:0016491 oxidoreductase activity Database 0


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