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Query: ETF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ETF1 1 5.212 -1.050 1.350 0.658 2.782 0.235 0.065

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ETF1 Ubiquitylation K249 -0.178 _LQSK(gl)VLK_
ETF1 Ubiquitylation K395 0.300 _FGATLEIVTDK(gl)SQEGSQFVK_

Background Information for ETF1:


Pubmed-ETF1 »
Uniprot-ETF1 »
Biogrid-ETF1 »
ProteomicsDB-ETF1 »

Tumorportal-ETF1 »
COSMIC-ETF1 »
GenomeRNAi-ETF1 »
Genecards-ETF1


Protein-protein Interactions for ETF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC38A7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ETF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members eRF1_1_Pelota IPR005140 0.26
Category members eRF1_2 IPR005141 0.26
Category members eRF1_3 IPR005142 0.26
Category members L30e-like IPR029064 0


Protein complexes (CORUM database) featuring ETF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 784 SMG-1-Upf1-eRF1-eRF3 complex (SURF) Database 0.08


Categories featuring ETF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0043022 ribosome binding Database 0.33
Category members GO Category GO:0016149 translation release factor activity, codon specific Database 0.07
Category members GO Category GO:0003747 translation release factor activity Database 0
Category members GO Category GO:0006449 regulation of translational termination Database 0
Category members GO Category GO:0006479 protein methylation Database 0


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