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Query: EP400

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EP400 2 4.002 0.540 -0.240 0.463 0.361 -0.654 -0.158
EP400 2 4.002 0.670 -0.140 0.463 0.361 -0.654 -0.158

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EP400 Phosphorylation S1547 2.058 1.932 _HQPASASSTAAS(ph)PAHPAK_
EP400 Phosphorylation S736 0.587 1.013 _ALS(ph)PVTSR_
EP400 Phosphorylation S1732 0.440 0.219 _VAVNALAVGEPGTASKPAS(ph)PIGGPTQEEK_
EP400 Phosphorylation T314 -0.269 _TPGVLLPGAGGAAGFGM(ox)T(ph)SPPPPT(ph)SPSR_
EP400 Phosphorylation S315 -0.906 _TPGVLLPGAGGAAGFGMTS(ph)PPPPTS(ph)PSR_
EP400 Phosphorylation S321 -1.918 _TPGVLLPGAGGAAGFGM(ox)TSPPPPTS(ph)PSR_
EP400 Phosphorylation T1738 0.268 _VAVNALAVGEPGTASKPASPIGGPT(ph)QEEK_

Background Information for EP400:





Protein-protein Interactions for EP400

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRRAP Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KAT5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EP400

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SNF2_N IPR000330 3.38
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members HAS_subgr IPR013999 0.68
Category members Helicase/SANT-assoc_DNA-bd IPR014012 0.68
Category members Myb-like_dom IPR017877 0.63
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring EP400

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1166 p400-associated complex Database 0.68
Category members Corum 2857 NuA4/Tip60 HAT complex Database 0.28
Category members Corum 798 NuA4/Tip60-HAT complex A Database 0.28
Category members Corum 2856 NuA4/Tip60 HAT complex Database 0.13
Category members Corum 528 NuA4/Tip60 HAT complex Database 0.07
Category members Corum 799 DMAP1-associated complex Database 0.05
Category members Corum 529 NuA4/Tip60 HAT complex Database 0.04


Categories featuring EP400

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0035267 NuA4 histone acetyltransferase complex Database 0.07
Category members GO Category GO:0043968 histone H2A acetylation Database 0.02
Category members GO Category GO:0043967 histone H4 acetylation Database 0


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