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Query: ENC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ENC1 0 1.284

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ENC1 Ubiquitylation K527 1.284 _VGDVTAK(gl)R_
ENC1 Ubiquitylation K318 -0.887 _AK(gl)EIIPK_

Background Information for ENC1:


Pubmed-ENC1 »
Uniprot-ENC1 »
Biogrid-ENC1 »
ProteomicsDB-ENC1 »

Tumorportal-ENC1 »
COSMIC-ENC1 »
GenomeRNAi-ENC1 »
Genecards-ENC1


Protein-protein Interactions for ENC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CUL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ENC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kelch_1 IPR006652 0.44
Category members BTB/POZ-like IPR000210 0.43
Category members BACK IPR011705 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32
Category members Kelch-like_gigaxonin-typ IPR017096 0.23
Category members Kelch_2 IPR011498 0.2


Protein complexes (CORUM database) featuring ENC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ENC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0010499 proteasomal ubiquitin-independent protein catabolic process Database 0
Category members GO Category GO:0031463 Cul3-RING ubiquitin ligase complex Database 0


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