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Query: ELF4

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ELF4 0 0.816 -0.110 0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ELF4 Phosphorylation S151 0.294 0.267 _AGDTS(ph)DQEGHSLEEK_
ELF4 Ubiquitylation K280 -0.045 _GILAK(gl)VEGQR_
ELF4 Phosphorylation S188 -0.602 -0.663 _STS(ph)PVTDPSIPIR_
ELF4 Phosphorylation S641 -1.056 _S(ph)PTPAPFSPFNPTSLIK_
ELF4 Ubiquitylation K245 -1.504 _LVDSK(gl)AVSK_

Background Information for ELF4:


Pubmed-ELF4 »
Uniprot-ELF4 »
Biogrid-ELF4 »
ProteomicsDB-ELF4 »

Tumorportal-ELF4 »
COSMIC-ELF4 »
GenomeRNAi-ELF4 »
Genecards-ELF4


Protein-protein Interactions for ELF4
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ELF4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ets_dom IPR000418 0.07
Category members TF_Elf_N IPR022084 0


Protein complexes (CORUM database) featuring ELF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ELF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Disease phenotype Short_stature_due_to_isolated_growth_hormone_deficiency_with_X-linked_hypogammaglobulinemia Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia Database 0
Category members GO Category GO:0001866 NK T cell proliferation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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