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Query: EIF3M

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF3M 0 1.768 -0.940 1.180 1.204 -0.204 -0.645 -0.242 0.453

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF3M Ubiquitylation K324 -1.257 0.916 _MVYCK(gl)IDQTQR_
EIF3M Phosphorylation S2 -0.586 0.874 _(ac)S(ph)VPAFIDISEEDQAAELR_
EIF3M Ubiquitylation K319 0.336 _TK(gl)MVYCK_
EIF3M Ubiquitylation K365 -1.182 _VK(gl)NSLLSLSDT_

Background Information for EIF3M:


Pubmed-EIF3M »
Uniprot-EIF3M »
Biogrid-EIF3M »
ProteomicsDB-EIF3M »

Tumorportal-EIF3M »
COSMIC-EIF3M »
GenomeRNAi-EIF3M »
Genecards-EIF3M


Protein-protein Interactions for EIF3M
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3F Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3H Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3I Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF3M
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members PCI_dom IPR000717 2.22


Protein complexes (CORUM database) featuring EIF3M
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) Database 1.41


Categories featuring EIF3M
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005852 eukaryotic translation initiation factor 3 complex Database 2.27
Category members GO Category GO:0033290 eukaryotic 48S preinitiation complex Database 1.41
Category members GO Category GO:0001731 formation of translation preinitiation complex Database 1.15
Category members GO Category GO:0016282 eukaryotic 43S preinitiation complex Database 1.15
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04


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