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Query: EIF3L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF3L 0 2.727 -0.220 0.210 1.283 -0.297 -0.632 0.472 0.378

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF3L Ubiquitylation K345 0.635 _VLENIELNKK(gl)_
EIF3L Ubiquitylation K249 0.678 _TAK(gl)KSEEEIDFLR_
EIF3L Ubiquitylation K446 0.248 _MQK(gl)GDPQVYEELFSYSCPK_
EIF3L Ubiquitylation K592 0.129 _QIHK(gl)FEELNR_

Background Information for EIF3L:


Pubmed-EIF3L »
Uniprot-EIF3L »
Biogrid-EIF3L »
ProteomicsDB-EIF3L »

Tumorportal-EIF3L »
COSMIC-EIF3L »
GenomeRNAi-EIF3L »
Genecards-EIF3L


Protein-protein Interactions for EIF3L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3F Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3H Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3I Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMD12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF3L
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring EIF3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1223 H2AX complex, isolated from cells without IR exposure Database 8.51
Category members Corum 742 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) Database 1.74
Category members Corum 1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) Database 1.41


Categories featuring EIF3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005852 eukaryotic translation initiation factor 3 complex Database 2.27
Category members GO Category GO:0033290 eukaryotic 48S preinitiation complex Database 1.41
Category members GO Category GO:0001731 formation of translation preinitiation complex Database 1.15
Category members GO Category GO:0016282 eukaryotic 43S preinitiation complex Database 1.15
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04


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