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Query: EIF3I

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF3I 0 1.849 0.110 0.120 0.928 -0.396 -0.648 0.140 0.141

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF3I Ubiquitylation K264 -1.679 0.171 _IGK(gl)FEAR_
EIF3I Ubiquitylation K85 -0.157 0.073 _LWDCETGK(gl)QLALLK_
EIF3I Ubiquitylation K91 -0.358 0.012 _QLALLK(gl)TNSAVR_
EIF3I Ubiquitylation K185 1.393 -0.352 _SGEVLVNVK(gl)EHSR_
EIF3I Ubiquitylation K213 -0.562 _DNTAK(gl)LFDSTTLEHQK_
EIF3I Ubiquitylation K224 -0.631 _LFDSTTLEHQK(gl)TFR_
EIF3I Ubiquitylation K17 -0.648 _SITQIK(gl)YNR_
EIF3I Ubiquitylation K2 -2.212 -0.783 _MK(gl)PILLQGHER_
EIF3I Ubiquitylation K282 -2.236 -0.906 _VK(gl)GHFGPINSVAFHPDGK_
EIF3I Ubiquitylation K208 -0.989 -1.151 _DMTMFVTASK(gl)DNTAK_

Background Information for EIF3I:


Pubmed-EIF3I »
Uniprot-EIF3I »
Biogrid-EIF3I »
ProteomicsDB-EIF3I »

Tumorportal-EIF3I »
COSMIC-EIF3I »
GenomeRNAi-EIF3I »
Genecards-EIF3I


Protein-protein Interactions for EIF3I
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITSN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait L1TD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CERKL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3G Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF3I
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring EIF3I
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 742 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) Database 1.74
Category members Corum 1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) Database 1.41
Category members Corum 4392 EIF3 complex (EIF3A, EIF3B, EIF3G, EIF3I, EIF3C) Database 0.43
Category members Corum 4389 EIF3 core complex (EIF3A, EIF3B, EIF3G, EIF3I) Database 0.18
Category members Corum 4399 EIF3 complex (EIF3B, EIF3J, EIF3I) Database 0.07
Category members Corum 4403 EIF3 complex (EIF3A, EIF3B, EIF3G, EIF3I, EIF3J) Database 0.05
Category members Corum 4395 EIF3 complex (EIF3B, EIF3G, EIF3I) Database 0


Categories featuring EIF3I
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_769 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_775 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 0 11.53
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005852 eukaryotic translation initiation factor 3 complex Database 2.27
Category members GO Category GO:0033290 eukaryotic 48S preinitiation complex Database 1.41
Category members GO Category GO:0001731 formation of translation preinitiation complex Database 1.15
Category members GO Category GO:0016282 eukaryotic 43S preinitiation complex Database 1.15
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04


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