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Query: EIF3D

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF3D 0 2.162 0.280 -0.040 1.162 -0.282 -0.573 0.404 -0.197

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF3D Ubiquitylation K426 0.950 _GAVIATELK(gl)NNSYK_
EIF3D Ubiquitylation K53 0.241 0.793 _VADWTGATYQDK(gl)R_
EIF3D Ubiquitylation K510 0.035 _YLILK(gl)DPNK_
EIF3D Ubiquitylation K431 0.031 _NNSYK(gl)LAR_
EIF3D Ubiquitylation K275 0.698 _VGSK(gl)LFFDKR_

Background Information for EIF3D:


Pubmed-EIF3D »
Uniprot-EIF3D »
Biogrid-EIF3D »
ProteomicsDB-EIF3D »

Tumorportal-EIF3D »
COSMIC-EIF3D »
GenomeRNAi-EIF3D »
Genecards-EIF3D


Protein-protein Interactions for EIF3D
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3F Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3H Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3I Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF4A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF3D
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring EIF3D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 742 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) Database 1.74
Category members Corum 1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) Database 1.41


Categories featuring EIF3D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_769 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_775 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 0 11.53
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005852 eukaryotic translation initiation factor 3 complex Database 2.27
Category members GO Category GO:0033290 eukaryotic 48S preinitiation complex Database 1.41
Category members GO Category GO:0001731 formation of translation preinitiation complex Database 1.15
Category members GO Category GO:0016282 eukaryotic 43S preinitiation complex Database 1.15
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0001732 formation of translation initiation complex Database 0.11
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04


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