bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: EFTUD2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EFTUD2 0 1.893 -0.620 1.440 -0.272 0.268
EFTUD2 0 1.893 -0.620 1.440 0.120 -0.527 -0.008
EFTUD2 0 1.893 -0.400 0.210 -0.272 0.268
EFTUD2 0 1.893 -0.400 0.210 0.120 -0.527 -0.008

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EFTUD2 Ubiquitylation K405 0.872 _TLDELGIHLTK(gl)EELK_

Background Information for EFTUD2:


Pubmed-EFTUD2 »
Uniprot-EFTUD2 »
Biogrid-EFTUD2 »
ProteomicsDB-EFTUD2 »

Tumorportal-EFTUD2 »
COSMIC-EFTUD2 »
GenomeRNAi-EFTUD2 »
Genecards-EFTUD2


Protein-protein Interactions for EFTUD2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCAS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait PQBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD2BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAPP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EFTUD2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ribosomal_S5_D2-typ_fold IPR020568 1.06
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members Transl_B-barrel IPR009000 0.24
Category members Transl_elong_EFG/EF2_IV IPR005517 0.11
Category members EFG_V IPR000640 0
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members EFG_III-V IPR009022 0


Protein complexes (CORUM database) featuring EFTUD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 1335 SNW1 complex Database 3.59
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring EFTUD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0015030 Cajal body Database 0.04


.

© Copyright Svejstrup Laboratory 2015