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Query: EEF1A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEF1A1 3 10.301 -2.440 4.720 0.419 0.515 -0.045

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEF1A1 Ubiquitylation K439 1.574 1.766 _QTVAVGVIK(gl)AVDKK_
EEF1A1 Ubiquitylation K392 3.396 1.562 _LEDGPK(gl)FLK_
EEF1A1 Ubiquitylation K179 0.979 1.385 _EVSTYIK(gl)K_
EEF1A1 Ubiquitylation K154 -0.473 0.931 _QLIVGVNK(gl)MDSTEPPYSQK_
EEF1A1 Ubiquitylation K165 -0.308 0.766 _MDSTEPPYSQK(gl)R_
EEF1A1 Ubiquitylation K255 0.195 0.556 _LPLQDVYK(gl)IGGIGTVPVGR_
EEF1A1 Ubiquitylation K385 -0.005 -0.068 _SGK(gl)KLEDGPK_
EEF1A1 Ubiquitylation K41 0.772 _TIEK(gl)FEK_
EEF1A1 Ubiquitylation K44 0.444 _TIEKFEK(gl)EAAEMGK_
EEF1A1 Ubiquitylation K172 1.197 _YEEIVK(gl)EVSTYIK_
EEF1A1 Ubiquitylation K215 1.280 _GWK(gl)VTRK_

Background Information for EEF1A1:


Pubmed-EEF1A1 »
Uniprot-EEF1A1 »
Biogrid-EEF1A1 »
ProteomicsDB-EEF1A1 »

Tumorportal-EEF1A1 »
COSMIC-EEF1A1 »
GenomeRNAi-EEF1A1 »
Genecards-EEF1A1


Protein-protein Interactions for EEF1A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXorf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait N6AMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EEF1A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Transl_B-barrel IPR009000 0.24
Category members Transl_elong_EF1A_euk/arc IPR004539 0.24
Category members Transl_elong_EFTu/EF1A_C IPR004160 0.01
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members Transl_elong_EF1A/Init_IF2_C IPR009001 0


Protein complexes (CORUM database) featuring EEF1A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 1335 SNW1 complex Database 3.59


Categories featuring EEF1A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005853 eukaryotic translation elongation factor 1 complex Database 0.6
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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