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Query: ECHS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ECHS1 0 1.767 -0.830 1.690 0.677 1.000 -1.645 0.647 0.048

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ECHS1 Ubiquitylation K204 -0.650 _ISAQDAK(gl)QAGLVSK_

Background Information for ECHS1:


Pubmed-ECHS1 »
Uniprot-ECHS1 »
Biogrid-ECHS1 »
ProteomicsDB-ECHS1 »

Tumorportal-ECHS1 »
COSMIC-ECHS1 »
GenomeRNAi-ECHS1 »
Genecards-ECHS1


Protein-protein Interactions for ECHS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ECHS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ECHS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Crotonase_core_superfam IPR001753 0.08
Category members ClpP/crotonase-like_dom IPR029045 0.08


Protein complexes (CORUM database) featuring ECHS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ECHS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_136 KEGG_LIMONENE_AND_PINENE_DEGRADATION 0 0.87
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members Pathway Pathway_134 KEGG_BETA_ALANINE_METABOLISM 0 0.49
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_37 KEGG_TRYPTOPHAN_METABOLISM 0 0.06
Category members Pathway Pathway_145 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION 0 0.05
Category members Pathway Pathway_19 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 0 0.04
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members GO Category GO:0004300 enoyl-CoA hydratase activity Database 0
Category members GO Category GO:0006635 fatty acid beta-oxidation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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