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Query: DTX3L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DTX3L 0 0.505 -0.430 0.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DTX3L Phosphorylation S221 0.260 0.175 _DSCIS(ph)PSEPETK_
DTX3L Phosphorylation S9 -0.301 0.141 _(ac)ASHLRPPS(ph)PLLVR_

Background Information for DTX3L:


Pubmed-DTX3L »
Uniprot-DTX3L »
Biogrid-DTX3L »
ProteomicsDB-DTX3L »

Tumorportal-DTX3L »
COSMIC-DTX3L »
GenomeRNAi-DTX3L »
Genecards-DTX3L


Protein-protein Interactions for DTX3L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DTX3L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DTX3L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring DTX3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DTX3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0010390 histone monoubiquitination Database 1.39
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members Pathway Pathway_892 KEGG_NOTCH_SIGNALING_PATHWAY 0 0


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