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Query: DTNA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DTNA 1 5.475 -1.480 2.950 -0.253

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DTNA Phosphorylation S642 1.088 0.986 _ELNSEVGS(ph)ETESNVDSEFAR_
DTNA Phosphorylation S459 0.932 _S(ph)APDISFTIDANK_
DTNA Phosphorylation S663 1.120 0.531 _TQFEDLVPS(ph)PTSEK_
DTNA Phosphorylation T505 -0.687 -0.627 _LEHEQASQPT(ph)PEK_
DTNA Ubiquitylation K7 0.672 _(ac)MIEDSGK(gl)R_

Background Information for DTNA:





Protein-protein Interactions for DTNA

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC101 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DMD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FYCO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMG20A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNTG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DTNA

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EF-hand_dom_typ1 IPR015153 0.22
Category members EF-hand_dom_typ2 IPR015154 0.22
Category members Znf_ZZ IPR000433 0.01
Category members Distrobrevin IPR017432 0


Protein complexes (CORUM database) featuring DTNA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DTNA

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0006941 striated muscle contraction Database 0.14
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members GO Category GO:0045202 synapse Database 0.06
Category members Disease phenotype Left_ventricular_noncompaction Left ventricular noncompaction Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007274 neuromuscular synaptic transmission Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0042995 cell projection Database 0


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