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Query: DRG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DRG1 0 -0.295 0.110 0.560 0.485 -0.351 -0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DRG1 Ubiquitylation K324 -0.441 _TTVEDFCMK(gl)IHK_
DRG1 Ubiquitylation K175 -1.029 _LNSK(gl)PPNIGFK_
DRG1 Ubiquitylation K46 -0.237 -1.134 _ELITPK(gl)GGGGGGPGEGFDVAK_
DRG1 Ubiquitylation K61 -0.803 -1.153 _GGGGGGPGEGFDVAK(gl)TGDAR_
DRG1 Ubiquitylation K183 -1.372 _LNSKPPNIGFKK(gl)_
DRG1 Ubiquitylation K186 -0.697 _DK(gl)GGINLTATCPQSELDAETVK_

Background Information for DRG1:


Pubmed-DRG1 »
Uniprot-DRG1 »
Biogrid-DRG1 »
ProteomicsDB-DRG1 »

Tumorportal-DRG1 »
COSMIC-DRG1 »
GenomeRNAi-DRG1 »
Genecards-DRG1


Protein-protein Interactions for DRG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DRG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GTP_binding_domain IPR006073 0.59
Category members Small_GTP-bd_dom IPR005225 0.32
Category members Fe2_transport_prot_B_N IPR011619 0.11
Category members TGS IPR004095 0
Category members TGS-like IPR012676 0


Protein complexes (CORUM database) featuring DRG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DRG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0015093 ferrous iron transmembrane transporter activity Database 0.11
Category members GO Category GO:0015684 ferrous iron transport Database 0.11
Category members GO Category GO:0005844 polysome Database 0.09


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