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Query: DPYSL4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DPYSL4 0 -0.258 1.540 -1.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DPYSL4 Ubiquitylation K368 -0.258 _MSMVWEK(gl)CVASGK_
DPYSL4 Ubiquitylation K258 -0.562 _VMSK(gl)GAADAIAQAK_
DPYSL4 Ubiquitylation K268 -0.934 _GAADAIAQAK(gl)R_
DPYSL4 Ubiquitylation K244 -1.168 _AVTIAK(gl)QANCPLYVTK_

Background Information for DPYSL4:


Pubmed-DPYSL4 »
Uniprot-DPYSL4 »
Biogrid-DPYSL4 »
ProteomicsDB-DPYSL4 »

Tumorportal-DPYSL4 »
COSMIC-DPYSL4 »
GenomeRNAi-DPYSL4 »
Genecards-DPYSL4


Protein-protein Interactions for DPYSL4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DEF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPYSL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPYSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DPYSL4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Hydantoinase/dihydroPyrase IPR011778 0.23
Category members Amidohydro_1 IPR006680 0
Category members Metal-dep_hydrolase_composite IPR011059 0


Protein complexes (CORUM database) featuring DPYSL4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DPYSL4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_674 REACTOME_SEMAPHORIN_INTERACTIONS 0 0.96
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0006208 pyrimidine nucleobase catabolic process Database 0.22
Category members Pathway Pathway_1282 REACTOME_CRMPS_IN_SEMA3A_SIGNALING 0 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Database 0.04
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Database 0
Category members GO Category GO:0048666 neuron development Database 0


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