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Query: DHX57

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHX57 0 1.881 -0.810 1.000 -0.088 -0.069

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHX57 Phosphorylation S127 0.794 0.244 _DLQEQDADAGS(ph)ER_
DHX57 Phosphorylation S132 0.051 0.181 _GLS(ph)GEEEDDEPDCCNDER_

Background Information for DHX57:


Pubmed-DHX57 »
Uniprot-DHX57 »
Biogrid-DHX57 »
ProteomicsDB-DHX57 »

Tumorportal-DHX57 »
COSMIC-DHX57 »
GenomeRNAi-DHX57 »
Genecards-DHX57


Protein-protein Interactions for DHX57
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait BHLHA15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHX57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FNTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEUROG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF323 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHX57
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Znf_CCCH IPR000571 0.03
Category members DUF1605 IPR011709 0.02
Category members RWD-domain IPR006575 0
Category members Helicase-assoc_dom IPR007502 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring DHX57
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHX57
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0046872 metal ion binding Database 0


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