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Query: DHX40

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHX40 1 -0.055 1.520 -0.990 0.363 -0.036 -0.375 0.087
DHX40 1 -0.055 2.010 -1.040 0.363 -0.036 -0.375 0.087

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHX40 Ubiquitylation K142 -0.803 0.695 _FDDCSSK(gl)ETAIK_
DHX40 Ubiquitylation K367 -0.315 _YVVDGGFVK(gl)QLNHNPR_
DHX40 Phosphorylation T78 0.332 -0.318 _DNSFLIVTGNT(ph)GSGKT(ph)T(ph)QLPK_
DHX40 Phosphorylation T83 0.332 -0.318 _DNSFLIVTGNT(ph)GSGKT(ph)T(ph)QLPK_
DHX40 Phosphorylation T84 0.332 -0.318 _DNSFLIVTGNT(ph)GSGKT(ph)T(ph)QLPK_

Background Information for DHX40:


Pubmed-DHX40 »
Uniprot-DHX40 »
Biogrid-DHX40 »
ProteomicsDB-DHX40 »

Tumorportal-DHX40 »
COSMIC-DHX40 »
GenomeRNAi-DHX40 »
Genecards-DHX40


Protein-protein Interactions for DHX40
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USP7 Cat. description Hein, Mann, Cell 2015
Category members IP bait ECE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPM2AIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHX40
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DUF1605 IPR011709 0.02
Category members T2SS_protein-E IPR001482 0
Category members Helicase-assoc_dom IPR007502 0


Protein complexes (CORUM database) featuring DHX40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHX40
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0006810 transport Database 0


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