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Query: DENND4C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DENND4C 0 1.829 -0.510 -0.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DENND4C Phosphorylation S989 1.475 _TPDSEDKLFS(ph)PVIAR_
DENND4C Phosphorylation S1089 0.588 0.764 _STS(ph)LSALVR_
DENND4C Phosphorylation S1008 0.340 0.577 _NLADEIESYMNLKS(ph)PLGSK_
DENND4C Phosphorylation S948 0.624 0.558 _RSS(ph)LYGIAK_
DENND4C Phosphorylation S863 0.409 0.348 _THS(ph)FENVSCHLPDSR_
DENND4C Phosphorylation S505 -0.139 _HPTGNSITKS(ph)PPLM(ox)AK_
DENND4C Phosphorylation S947 -0.290 _RS(ph)SLYGIAK_
DENND4C Phosphorylation S1042 -0.176 -0.344 _RSS(ph)LPLDHGSPAQENPESEK_
DENND4C Phosphorylation S889 -1.060 -1.281 _S(ph)SPVPEM(ox)LEESQELLEPVVDDVPK_
DENND4C Phosphorylation S890 -1.281 _S(ph)SPVPEM(ox)LEESQELLEPVVDDVPK_
DENND4C Phosphorylation S1041 -0.298 _RS(ph)SLPLDHGSPAQENPESEK_

Background Information for DENND4C:


Pubmed-DENND4C »
Uniprot-DENND4C »
Biogrid-DENND4C »
ProteomicsDB-DENND4C »

Tumorportal-DENND4C »
COSMIC-DENND4C »
GenomeRNAi-DENND4C »
Genecards-DENND4C


Protein-protein Interactions for DENND4C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1orf112 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait ECD Cat. description Hein, Mann, Cell 2015
Category members IP bait PQBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TGS1 Cat. description Hein, Mann, Cell 2015


Protein Domains in DENND4C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DENN_dom IPR001194 0
Category members dDENN_dom IPR005112 0
Category members uDENN_dom IPR005113 0


Protein complexes (CORUM database) featuring DENND4C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DENND4C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0030904 retromer complex Database 0.14
Category members GO Category GO:0017112 Rab guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0032593 insulin-responsive compartment Database 0


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