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Query: DEGS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DEGS1 0 0.183 -0.840 0.770

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DEGS1 Ubiquitylation K317 -0.703 0.116 _HQK(gl)GEMVLE_
DEGS1 Ubiquitylation K29 -1.129 -0.103 _EILAK(gl)YPEIK_

Background Information for DEGS1:


Pubmed-DEGS1 »
Uniprot-DEGS1 »
Biogrid-DEGS1 »
ProteomicsDB-DEGS1 »

Tumorportal-DEGS1 »
COSMIC-DEGS1 »
GenomeRNAi-DEGS1 »
Genecards-DEGS1


Protein-protein Interactions for DEGS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPLX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEGS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTH1R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCARA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIRT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DEGS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sphingolipid_d4-desaturase IPR011388 0.08
Category members Sphingolipid_d4-desaturase_N IPR013866 0.08
Category members Fatty_acid_desaturase-1 IPR005804 0


Protein complexes (CORUM database) featuring DEGS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DEGS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006636 unsaturated fatty acid biosynthetic process Database 0.07
Category members GO Category GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Database 0.05
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0030148 sphingolipid biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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