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Query: DDX18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX18 1 2.159 1.140 -0.730 -0.072 0.158

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX18 Ubiquitylation K7 2.073 _(ac)SHLPMK(gl)LLR_
DDX18 Ubiquitylation K224 1.297 _DLLAAAK(gl)TGSGK_

Background Information for DDX18:


Pubmed-DDX18 »
Uniprot-DDX18 »
Biogrid-DDX18 »
ProteomicsDB-DDX18 »

Tumorportal-DDX18 »
COSMIC-DDX18 »
GenomeRNAi-DDX18 »
Genecards-DDX18


Protein-protein Interactions for DDX18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35


Protein complexes (CORUM database) featuring DDX18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DDX18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79


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