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Query: CYFIP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CYFIP2 0 0.061 1.310 -0.900
CYFIP2 0 0.061 1.310 -0.900 -0.549 -0.254
CYFIP2 0 0.061 1.310 -0.900 0.342 0.525

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CYFIP2 Ubiquitylation K802 -0.138 _ISAAMYK(gl)SLDQAISR_
CYFIP2 Ubiquitylation K1107 -1.397 -0.576 _EGDLLTK(gl)ER_
CYFIP2 Ubiquitylation K775 -0.646 _YETLLK(gl)QR_
CYFIP2 Ubiquitylation K545 -0.918 _GGFDIK(gl)VPR_
CYFIP2 Ubiquitylation K97 0.135 _AIPQVK(gl)CNEQPNRVEIYEK_

Background Information for CYFIP2:


Pubmed-CYFIP2 »
Uniprot-CYFIP2 »
Biogrid-CYFIP2 »
ProteomicsDB-CYFIP2 »

Tumorportal-CYFIP2 »
COSMIC-CYFIP2 »
GenomeRNAi-CYFIP2 »
Genecards-CYFIP2


Protein-protein Interactions for CYFIP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LHX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NHSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIMM50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WASF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF511 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CYFIP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Chemokine_IL8-like_dom IPR001811 0
Category members DUF1394 IPR009828 0


Protein complexes (CORUM database) featuring CYFIP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CYFIP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members GO Category GO:0006955 immune response Database 1.22
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0008009 chemokine activity Database 0.03
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0


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