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Query: CYFIP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CYFIP1 0 -0.902 -1.358 0.258 0.198

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CYFIP1:


Pubmed-CYFIP1 »
Uniprot-CYFIP1 »
Biogrid-CYFIP1 »
ProteomicsDB-CYFIP1 »

Tumorportal-CYFIP1 »
COSMIC-CYFIP1 »
GenomeRNAi-CYFIP1 »
Genecards-CYFIP1


Protein-protein Interactions for CYFIP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARX Cat. description Hein, Mann, Cell 2015
Category members IP bait BAIAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF2E2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NHSL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNA Cat. description Hein, Mann, Cell 2015
Category members IP bait TOR1AIP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NHSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIMM50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WASF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF511 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CYFIP1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CYFIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 186 Wave-2 complex Database 0.08
Category members Corum 2300 Profilin 2 complex Database 0


Categories featuring CYFIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0030032 lamellipodium assembly Database 0.66
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0048675 axon extension Database 0.01
Category members GO Category GO:0005845 mRNA cap binding complex Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0031529 ruffle organization Database 0


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