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Query: CRTC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CRTC2 0 2.109 0.400 -0.510

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CRTC2 Phosphorylation S624 0.924 1.185 _HGSGPNIILTGDSS(ph)PGFSK_
CRTC2 Phosphorylation S433 -0.257 -0.277 _VPLS(ph)PLSLLAGPADAR_
CRTC2 Phosphorylation S70 -0.644 -0.363 _SSHYGGS(ph)LPNVNQIGSGLAEFQSPLHSPLDSSR_

Background Information for CRTC2:


Pubmed-CRTC2 »
Uniprot-CRTC2 »
Biogrid-CRTC2 »
ProteomicsDB-CRTC2 »

Tumorportal-CRTC2 »
COSMIC-CRTC2 »
GenomeRNAi-CRTC2 »
Genecards-CRTC2


Protein-protein Interactions for CRTC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait CRTC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDYHV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CRTC2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CRTC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CRTC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0008140 cAMP response element binding protein binding Database 0.3
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0032793 positive regulation of CREB transcription factor activity Database 0


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