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Query: CPSF4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CPSF4 0 0.349 -0.220 0.390 0.323 -0.195 0.805 -0.308 0.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CPSF4 Phosphorylation S200 0.618 0.477 _S(ph)SSLIQLTSQNSSPNQQR_
CPSF4 Phosphorylation S211 0.740 0.194 _SSS(ph)LIQLTSQNS(ph)SPNQQR_
CPSF4 Phosphorylation S202 0.627 -0.110 _SSS(ph)LIQLTSQNS(ph)SPNQQR_
CPSF4 Ubiquitylation K51 -1.354 -0.800 _AACGK(gl)GGMCPFR_

Background Information for CPSF4:


Pubmed-CPSF4 »
Uniprot-CPSF4 »
Biogrid-CPSF4 »
ProteomicsDB-CPSF4 »

Tumorportal-CPSF4 »
COSMIC-CPSF4 »
GenomeRNAi-CPSF4 »
Genecards-CPSF4


Protein-protein Interactions for CPSF4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CPSF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FIP1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYMPK Cat. description Hein, Mann, Cell 2015
Category members IP bait CPSF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTRA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CPSF4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_CCHC IPR001878 1.51
Category members Znf_CCCH IPR000571 0.03


Protein complexes (CORUM database) featuring CPSF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1144 Cleavage and polyadenylation factor (CPSF) Database 0.01


Categories featuring CPSF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005847 mRNA cleavage and polyadenylation specificity factor complex Database 0.11
Category members GO Category GO:0019054 modulation by virus of host process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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