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Query: CPSF3L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CPSF3L 2 -1.877 -0.680 0.900
CPSF3L 2 -1.877 -0.680 0.900 -1.333 1.740 2.321 -4.714 -0.284

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CPSF3L Ubiquitylation K492 -0.507 _LLHGTLIM(ox)K(gl)DSNFR_
CPSF3L Ubiquitylation K295 -1.274 _LFIPWTNQK(gl)IR_
CPSF3L Ubiquitylation K480 -1.788 _EMAQGLLPEAK(gl)KPR_

Background Information for CPSF3L:


Pubmed-CPSF3L »
Uniprot-CPSF3L »
Biogrid-CPSF3L »
ProteomicsDB-CPSF3L »

Tumorportal-CPSF3L »
COSMIC-CPSF3L »
GenomeRNAi-CPSF3L »
Genecards-CPSF3L


Protein-protein Interactions for CPSF3L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait INTS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait NABP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CPSF3L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Beta-lactamas-like IPR001279 0
Category members RMMBL IPR011108 0
Category members Beta_Casp IPR022712 0


Protein complexes (CORUM database) featuring CPSF3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1155 Integrator-RNAPII complex Database 5.97
Category members Corum 1153 Integrator complex Database 4.67
Category members Corum 1154 DSS1 complex Database 1.97


Categories featuring CPSF3L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016787 hydrolase activity Database 0.22


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