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Query: CHMP4B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHMP4B 1 2.933 0.110 0.340

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHMP4B Ubiquitylation K17 -0.147 0.040 _AGK(gl)GGPTPQEAIQR_
CHMP4B Ubiquitylation K6 0.858 _(ac)SVFGK(gl)LFGAGGGK_
CHMP4B Ubiquitylation K39 0.591 _LRDTEEMLSKK(gl)_
CHMP4B Ubiquitylation K45 1.027 _KQEFLEK(gl)K_
CHMP4B Ubiquitylation K56 0.362 _KIEQELTAAKK(gl)_
CHMP4B Ubiquitylation K70 2.554 _AALQALK(gl)R_
CHMP4B Ubiquitylation K107 0.634 _EALENANTNTEVLK(gl)NMGYAAK_
CHMP4B Ubiquitylation K114 0.459 _NMGYAAK(gl)AMK_

Background Information for CHMP4B:


Pubmed-CHMP4B »
Uniprot-CHMP4B »
Biogrid-CHMP4B »
ProteomicsDB-CHMP4B »

Tumorportal-CHMP4B »
COSMIC-CHMP4B »
GenomeRNAi-CHMP4B »
Genecards-CHMP4B


Protein-protein Interactions for CHMP4B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait BAZ2B Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP2A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DAXX Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TAOK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSG101 Cat. description Hein, Mann, Cell 2015
Category members IP bait VCP Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015


Protein Domains in CHMP4B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Snf7 IPR005024 0.58


Protein complexes (CORUM database) featuring CHMP4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1186 ESCRT-III complex Database 0.85


Categories featuring CHMP4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0030496 midbody Database 0.39
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members Disease phenotype Posterior_polar_cataract Posterior polar cataract Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0


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