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bioLOGIC Data

Query: CHMP2A

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
CHMP2A	0	1.050

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
CHMP2A	Ubiquitylation	K94	0.439	0.611	_IQTLK(gl)SNNSMAQAMK_
CHMP2A	Ubiquitylation	K52	0.105		_MAK(gl)QGQMDAVR_
CHMP2A	Ubiquitylation	K108	0.133		_GVTK(gl)AMGTMNR_

Background Information for CHMP2A:

Pubmed-CHMP2A »

Uniprot-CHMP2A »

Biogrid-CHMP2A »

ProteomicsDB-CHMP2A »

Tumorportal-CHMP2A »

COSMIC-CHMP2A »

GenomeRNAi-CHMP2A »

Genecards-CHMP2A

Protein-protein Interactions for CHMP2A

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ATP6AP2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CD2AP	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CEP55	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CHMP2A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CHMP4B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CORO1C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PTPN23	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RAB2A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RAB5C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RAB7A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RANBP2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RING1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SPAST	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TFG	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait VPS4B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CCDC83	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CHMP2A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait OSTF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SIX2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SNAP23	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SPAST	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait STAMBP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in CHMP2A

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Snf7	IPR005024	0.58

Protein complexes (CORUM database) featuring CHMP2A

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	1186	ESCRT-III complex	Database	0.85

Categories featuring CHMP2A

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0016032	viral process	Database	INF
Category members	GO Category	GO:0015031	protein transport	Database	3.48
Category members	GO Category	GO:0019904	protein domain specific binding	Database	1.85
Category members	Pathway	Pathway_666	KEGG_ENDOCYTOSIS	0	1.25
Category members	Pathway	Pathway_474	REACTOME_MEMBRANE_TRAFFICKING	0	1.14
Category members	GO Category	GO:0016197	endosomal transport	Database	0.43
Category members	Pathway	Pathway_800	REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT	0	0.06
Category members	GO Category	GO:0031902	late endosome membrane	Database	0