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Query: CHFR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHFR 2 8.109 -1.430 1.990

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHFR Ubiquitylation K86 2.204 2.485 _SGQVTLEDTSTSGTVINK(gl)LK_
CHFR Phosphorylation S10 1.431 _(ac)MERPEEGKQS(ph)PPPQPWGR_

Background Information for CHFR:


Pubmed-CHFR »
Uniprot-CHFR »
Biogrid-CHFR »
ProteomicsDB-CHFR »

Tumorportal-CHFR »
COSMIC-CHFR »
GenomeRNAi-CHFR »
Genecards-CHFR


Protein-protein Interactions for CHFR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C5orf24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CHFR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FHA_dom IPR000253 2.3
Category members SMAD_FHA_domain IPR008984 0.86
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring CHFR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CHFR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0019941 modification-dependent protein catabolic process Database 0


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