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Query: CHAF1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHAF1B 0 1.330 0.200 0.010 0.584 -0.122 0.442 0.170 0.125

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHAF1B Phosphorylation S428 0.028 _TQDPS(ph)SPGTTPPQAR_
CHAF1B Phosphorylation S429 -0.132 0.009 _TQDPSS(ph)PGTTPPQAR_
CHAF1B Phosphorylation T419 -0.292 _GSSPGPRPVEGT(ph)PASR_
CHAF1B Phosphorylation S410 -0.648 -0.454 _GSS(ph)PGPRPVEGTPASR_
CHAF1B Phosphorylation T433 -0.509 -0.478 _TQDPSS(ph)PGTT(ph)PPQAR_
CHAF1B Phosphorylation S409 -0.478 -0.616 _GS(ph)SPGPRPVEGTPASR_
CHAF1B Ubiquitylation K203 0.235 _VYSIQKK(gl)_

Background Information for CHAF1B:


Pubmed-CHAF1B »
Uniprot-CHAF1B »
Biogrid-CHAF1B »
ProteomicsDB-CHAF1B »

Tumorportal-CHAF1B »
COSMIC-CHAF1B »
GenomeRNAi-CHAF1B »
Genecards-CHAF1B


Protein-protein Interactions for CHAF1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AFF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait LRIF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CHAF1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Gprotein_B IPR001632 0


Protein complexes (CORUM database) featuring CHAF1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1259 Chromatin assembly complex (CAF-1 complex) Database 0.35
Category members Corum 2234 Chromatin assembly complex (CAF-1 complex) Database 0.35
Category members Corum 2236 ASF1-histone containing complex Database 0.04
Category members Corum 2235 ASF1-interacting protein complex Database 0


Categories featuring CHAF1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0033186 CAF-1 complex Database 0.35
Category members GO Category GO:0006335 DNA replication-dependent nucleosome assembly Database 0.13
Category members GO Category GO:0031497 chromatin assembly Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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