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Query: CENPH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CENPH 0 0.975 -0.100 0.260

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CENPH Ubiquitylation K118 -0.267 0.806 _NLEK(gl)ISR_
CENPH Ubiquitylation K100 0.269 _VAFEIKK(gl)_
CENPH Ubiquitylation K51 -0.970 0.071 _AQTK(gl)QQLLEYK_
CENPH Ubiquitylation K165 -0.023 -0.208 _LQLK(gl)QASESK_
CENPH Phosphorylation S16 -0.343 -0.291 _(ac)M(ox)EEQPQMQDADEPADS(ph)GGEGR_
CENPH Ubiquitylation K181 0.543 _LLEIQTEKNK(gl)_

Background Information for CENPH:


Pubmed-CENPH »
Uniprot-CENPH »
Biogrid-CENPH »
ProteomicsDB-CENPH »

Tumorportal-CENPH »
COSMIC-CENPH »
GenomeRNAi-CENPH »
Genecards-CENPH


Protein-protein Interactions for CENPH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPH Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPI Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPO Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait ACOX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSPRY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC107 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC151 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GGA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ING2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMAN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEKT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CENPH
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CENPH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 929 CEN complex Database 3.25
Category members Corum 1179 CENP-A NAC-CAD complex Database 0
Category members Corum 927 CENP-A nucleosome associated complex Database 0


Categories featuring CENPH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0043515 kinetochore binding Database 0
Category members GO Category GO:0051382 kinetochore assembly Database 0
Category members GO Category GO:0051383 kinetochore organization Database 0


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