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Query: CDCA5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDCA5 0 -3.077 0.610 -0.480 -0.367 -1.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDCA5 Phosphorylation S21 -0.766 -0.654 _APS(ph)PTKPLR_

Background Information for CDCA5:


Pubmed-CDCA5 »
Uniprot-CDCA5 »
Biogrid-CDCA5 »
ProteomicsDB-CDCA5 »

Tumorportal-CDCA5 »
COSMIC-CDCA5 »
GenomeRNAi-CDCA5 »
Genecards-CDCA5


Protein-protein Interactions for CDCA5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD21 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDCA5
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CDCA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1856 CDCA5-PDS5A-RAD21-SMC1A-PDS5B-SMC3 complex Database 1.25
Category members Corum 5432 Sororin-cohesin complex Database 1.25


Categories featuring CDCA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0005694 chromosome Database 3.87
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0008278 cohesin complex Database 0.44
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0007080 mitotic metaphase plate congression Database 0.04
Category members GO Category GO:0007064 mitotic sister chromatid cohesion Database 0.03
Category members GO Category GO:0007076 mitotic chromosome condensation Database 0.01
Category members GO Category GO:0051329 mitotic interphase Database 0


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