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Query: CD2BP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD2BP2 0 1.588 -1.240 2.040 -0.958 0.568 0.419

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD2BP2 Phosphorylation S49 0.560 0.641 _HSLDS(ph)DEEEDDDDGGSSK_
CD2BP2 Phosphorylation S195 -0.075 0.078 _KGPGQPSS(ph)PQRLDR_
CD2BP2 Phosphorylation S194 -0.445 0.042 _KGPGQPS(ph)SPQRLDR_
CD2BP2 Phosphorylation S247 -1.874 -2.011 _GLGCQTLGPHNPTPPPS(ph)LDM(ox)FAEELAEEELETPTPTQR_
CD2BP2 Phosphorylation T243 -2.298 _GLGCQTLGPHNPT(ph)PPPSLDMFAEELAEEELETPTPTQR_
CD2BP2 Ubiquitylation K333 -1.682 _KLDPPGGQFYNSK(gl)R_

Background Information for CD2BP2:


Pubmed-CD2BP2 »
Uniprot-CD2BP2 »
Biogrid-CD2BP2 »
ProteomicsDB-CD2BP2 »

Tumorportal-CD2BP2 »
COSMIC-CD2BP2 »
GenomeRNAi-CD2BP2 »
Genecards-CD2BP2


Protein-protein Interactions for CD2BP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF22 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait SART1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAPP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CD2BP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GYF IPR003169 0.11


Protein complexes (CORUM database) featuring CD2BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring CD2BP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005682 U5 snRNP Database 0.57
Category members GO Category GO:0000244 spliceosomal tri-snRNP complex assembly Database 0.15
Category members GO Category GO:0010923 negative regulation of phosphatase activity Database 0
Category members GO Category GO:0043021 ribonucleoprotein complex binding Database 0


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