bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: CCDC6

This is a cancer-associated gene according to the Broad and Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CCDC6 0 1.096 1.060 -0.980

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CCDC6 Phosphorylation S323 1.030 _QLS(ph)ESESSLEMDDER_
CCDC6 Phosphorylation S52 0.504 0.599 _SGGIVIS(ph)PFR_
CCDC6 Phosphorylation S419 -0.143 0.073 _RSNS(ph)PDKFK_
CCDC6 Phosphorylation S244 -0.079 -0.112 _LDQPVSAPPS(ph)PR_
CCDC6 Phosphorylation S240 -0.408 -0.213 _LDQPVS(ph)APPS(ph)PR_
CCDC6 Phosphorylation S367 -0.347 _PIS(ph)PGLSYASHTVGFTPPTSLTR_
CCDC6 Ubiquitylation K266 -0.865 -0.784 _FLK(gl)NEVER_
CCDC6 Ubiquitylation K83 0.346 _IELETYKLK(gl)_
CCDC6 Ubiquitylation K234 -0.604 _ILQEK(gl)LDQPVSAPPSPR_
CCDC6 Phosphorylation S351 -0.822 _TVS(ph)SPIPYTPSPSSSR_
CCDC6 Phosphorylation S417 0.106 _RS(ph)NSPDKFK_

Background Information for CCDC6:


Pubmed-CCDC6 »
Uniprot-CCDC6 »
Biogrid-CCDC6 »
ProteomicsDB-CCDC6 »

Tumorportal-CCDC6 »
COSMIC-CCDC6 »
GenomeRNAi-CCDC6 »
Genecards-CCDC6


Protein-protein Interactions for CCDC6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1S Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAFF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTUS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NECAB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP2CB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP4R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRPC4AP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF331 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF444 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CCDC6
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CCDC6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CCDC6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members Disease phenotype THYROID_CARCINOMA_PAPILLARY THYROID CARCINOMA PAPILLARY Database 0.72
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Disease phenotype Papillary_or_follicular_thyroid_carcinoma Papillary or follicular thyroid carcinoma Database 0.09
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_944 KEGG_THYROID_CANCER 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0


.

© Copyright Svejstrup Laboratory 2015