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Query: CAST

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAST 0 1.156 0.610 0.030

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAST Phosphorylation S425 0.387 0.769 _S(ph)ESELIDELSEDFDR_
CAST Phosphorylation S427 0.163 0.634 _SES(ph)ELIDELSEDFDR_
CAST Phosphorylation S2 -1.124 0.598 _(ac)S(ph)QPGQKPAAS(ph)PRPR_
CAST Phosphorylation S304 -0.616 -0.367 _KEGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGK_
CAST Phosphorylation S11 -0.654 -0.527 _(ac)S(ph)QPGQKPAAS(ph)PRPR_

Background Information for CAST:


Pubmed-CAST »
Uniprot-CAST »
Biogrid-CAST »
ProteomicsDB-CAST »

Tumorportal-CAST »
COSMIC-CAST »
GenomeRNAi-CAST »
Genecards-CAST


Protein-protein Interactions for CAST
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF13B Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPNS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FNTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTUS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAST
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CAST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CAST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0010951 negative regulation of endopeptidase activity Database 0
Category members GO Category GO:0004866 endopeptidase inhibitor activity Database 0
Category members GO Category GO:0004869 cysteine-type endopeptidase inhibitor activity Database 0
Category members GO Category GO:0010466 negative regulation of peptidase activity Database 0


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