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Query: CARS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CARS2 0 0.932 -1.640 2.050 -0.309 -0.735

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CARS2 Ubiquitylation K382 -0.074 _AYMK(gl)GQLACGSVR_

Background Information for CARS2:


Pubmed-CARS2 »
Uniprot-CARS2 »
Biogrid-CARS2 »
ProteomicsDB-CARS2 »

Tumorportal-CARS2 »
COSMIC-CARS2 »
GenomeRNAi-CARS2 »
Genecards-CARS2


Protein-protein Interactions for CARS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C13orf15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT61B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CARS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members aa-tRNA-synth_Ia IPR002300 0
Category members tRNAsynth_1a_anticodon-bd IPR009080 0
Category members Methionyl/Leucyl_tRNA_Synth IPR015413 0
Category members Cys-tRNA-ligase IPR015803 0
Category members Cys-tRNA/MSH_ligase IPR024909 0


Protein complexes (CORUM database) featuring CARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members GO Category GO:0004817 cysteine-tRNA ligase activity Database 0
Category members GO Category GO:0004824 lysine-tRNA ligase activity Database 0
Category members GO Category GO:0006423 cysteinyl-tRNA aminoacylation Database 0
Category members GO Category GO:0006430 lysyl-tRNA aminoacylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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