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Query: CA12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CA12 0 1.830 -0.870 1.360

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CA12 Ubiquitylation K347 0.260 0.210 _GVIYKPATK(gl)METEAHA_
CA12 Ubiquitylation K343 0.076 _GVIYK(gl)PATK_

Background Information for CA12:





Protein-protein Interactions for CA12

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CA12

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Carbonic_anhydrase_a IPR001148 0


Protein complexes (CORUM database) featuring CA12

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CA12

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Pathway Pathway_393 KEGG_NITROGEN_METABOLISM 0 0.07
Category members Pathway Pathway_752 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE 0 0
Category members GO Category GO:0004089 carbonate dehydratase activity Database 0
Category members GO Category GO:0006730 one-carbon metabolic process Database 0
Category members GO Category GO:0015701 bicarbonate transport Database 0


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