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Query: BRWD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRWD1 2 8.377 -0.840 0.680 0.190 -0.563
BRWD1 2 8.377 -0.840 0.680 0.434 0.305

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRWD1 Phosphorylation S1315 2.743 1.429 _AQS(ph)YDIQAWKK_
BRWD1 Ubiquitylation K1062 1.216 0.801 _QQFDDAK(gl)YRR_
BRWD1 Phosphorylation S1783 0.754 0.729 _TAFYNEDDS(ph)EEEQR_
BRWD1 Phosphorylation S674 0.709 0.567 _LSRGS(ph)ISSTSEVHSPPNVGLR_
BRWD1 Phosphorylation S1560 -0.176 0.420 _ALNTLSS(ph)PGQSSFSHGTR_
BRWD1 Ubiquitylation K1815 1.427 0.364 _AK(gl)ANLIGW_
BRWD1 Phosphorylation S1651 -0.008 _VEVNTNS(ph)GEIIHK_
BRWD1 Phosphorylation S911 0.029 -0.103 _VNEEKDGPIS(ph)PKK_
BRWD1 Phosphorylation S1525 -0.688 _VVVDPVVTEQPSTSS(ph)AAK_
BRWD1 Ubiquitylation K6 1.214 _K(gl)GLSELR_
BRWD1 Ubiquitylation K65 0.460 _TYQNLVK(gl)YYR_
BRWD1 Ubiquitylation K767 0.459 _ENK(gl)IPTVSK_
BRWD1 Ubiquitylation K1005 0.642 _EQELMK(gl)IVGIK_
BRWD1 Ubiquitylation K1032 -0.023 _LAFLDPDTGK(gl)LTGGSFTMK_
BRWD1 Ubiquitylation K1383 -0.669 _ETLEAGNYESPMELCK(gl)DVR_
BRWD1 Ubiquitylation K1528 -0.207 _VVVDPVVTEQPSTSSAAK(gl)TFITK_
BRWD1 Ubiquitylation K1533 1.039 _TFITK(gl)ANASAIPGK_
BRWD1 Ubiquitylation K1602 1.984 _ASTLSK(gl)SSAVIEQGDCK_
BRWD1 Phosphorylation S1475 -0.364 _IIPELVGS(ph)PTQSTSSR_

Background Information for BRWD1:


Pubmed-BRWD1 »
Uniprot-BRWD1 »
Biogrid-BRWD1 »
ProteomicsDB-BRWD1 »

Tumorportal-BRWD1 »
COSMIC-BRWD1 »
GenomeRNAi-BRWD1 »
Genecards-BRWD1


Protein-protein Interactions for BRWD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATRX Cat. description Hein, Mann, Cell 2015
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait LIN28A Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015


Protein Domains in BRWD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring BRWD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BRWD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0


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