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Query: BRPF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRPF1 0 0.909 0.670 -0.500 0.533 0.529

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRPF1 Phosphorylation T920 -0.140 _ESQMT(ph)PSHGGSPVGPPQLPIMSSLR_
BRPF1 Phosphorylation S926 -0.328 _ESQMTPSHGGS(ph)PVGPPQLPIMSSLR_
BRPF1 Phosphorylation S922 -0.495 _ESQMTPS(ph)HGGSPVGPPQLPIMSSLR_
BRPF1 Phosphorylation S860 -0.013 _DGQTDS(ph)AAEESSSQETSK_

Background Information for BRPF1:


Pubmed-BRPF1 »
Uniprot-BRPF1 »
Biogrid-BRPF1 »
ProteomicsDB-BRPF1 »

Tumorportal-BRPF1 »
COSMIC-BRPF1 »
GenomeRNAi-BRPF1 »
Genecards-BRPF1


Protein-protein Interactions for BRPF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAZ2B Cat. description Hein, Mann, Cell 2015
Category members IP bait BRD2;DKFZp313H139 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC73 Cat. description Hein, Mann, Cell 2015
Category members IP bait GNPNAT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ING4 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2C Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BRPF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_C2H2 IPR007087 0.92
Category members Znf_PHD-finger IPR019787 0.91
Category members PWWP_dom IPR000313 0.63
Category members Enhancer_polycomb-like_N IPR019542 0.31


Protein complexes (CORUM database) featuring BRPF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2859 ING5 complex Database 0.56


Categories featuring BRPF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0070776 MOZ/MORF histone acetyltransferase complex Database 0.45
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043966 histone H3 acetylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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