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Query: BRK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRK1 0 -1.284 -0.250 -0.050

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRK1 Ubiquitylation K70 0.082 _VTK(gl)GETLT_
BRK1 Ubiquitylation K31 -1.316 _EYIEIITSSIKK(gl)_

Background Information for BRK1:


Pubmed-BRK1 »
Uniprot-BRK1 »
Biogrid-BRK1 »
ProteomicsDB-BRK1 »

Tumorportal-BRK1 »
COSMIC-BRK1 »
GenomeRNAi-BRK1 »
Genecards-BRK1


Protein-protein Interactions for BRK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015


Protein Domains in BRK1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring BRK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 186 Wave-2 complex Database 0.08


Categories featuring BRK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0048870 cell motility Database 0


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