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Query: BRD8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRD8 0 0.165
BRD8 0 0.165 -1.397 -0.390

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRD8 Phosphorylation T16 0.830 0.990 _(ac)MAT(ph)GT(ph)GKHKLLSTGPT(ph)EPWS(ph)IR_
BRD8 Phosphorylation S20 0.830 0.990 _(ac)MAT(ph)GT(ph)GKHKLLSTGPT(ph)EPWS(ph)IR_
BRD8 Phosphorylation T3 0.830 0.931 _(ac)MAT(ph)GT(ph)GKHKLLSTGPT(ph)EPWS(ph)IR_
BRD8 Phosphorylation T5 0.830 0.931 _(ac)MAT(ph)GT(ph)GKHKLLSTGPT(ph)EPWS(ph)IR_
BRD8 Phosphorylation S284 0.635 0.186 _GSLLPTS(ph)PR_
BRD8 Phosphorylation T283 0.619 0.123 _KGSLLPT(ph)SPR_
BRD8 Phosphorylation S268 -0.479 -0.431 _AT(ph)PPPS(ph)PLLSELLK_
BRD8 Phosphorylation S652 -0.627 _TEAS(ph)PESMLSPSHGSNPIEDPLEAETQHK_
BRD8 Phosphorylation T264 -1.015 -0.798 _AT(ph)PPPSPLLSELLK_
BRD8 Ubiquitylation K149 0.132 _LDELCNDIATKK(gl)_

Background Information for BRD8:


Pubmed-BRD8 »
Uniprot-BRD8 »
Biogrid-BRD8 »
ProteomicsDB-BRD8 »

Tumorportal-BRD8 »
COSMIC-BRD8 »
GenomeRNAi-BRD8 »
Genecards-BRD8


Protein-protein Interactions for BRD8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRRAP Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KAT5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BRD8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members Peptidase_M20_dimer IPR011650 0


Protein complexes (CORUM database) featuring BRD8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2857 NuA4/Tip60 HAT complex Database 0.28
Category members Corum 798 NuA4/Tip60-HAT complex A Database 0.28
Category members Corum 2856 NuA4/Tip60 HAT complex Database 0.13
Category members Corum 528 NuA4/Tip60 HAT complex Database 0.07
Category members Corum 799 DMAP1-associated complex Database 0.05
Category members Corum 529 NuA4/Tip60 HAT complex Database 0.04


Categories featuring BRD8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0035267 NuA4 histone acetyltransferase complex Database 0.07
Category members GO Category GO:0043968 histone H2A acetylation Database 0.02
Category members GO Category GO:0004887 thyroid hormone receptor activity Database 0.01
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0043967 histone H4 acetylation Database 0


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