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Query: AZGP1

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AZGP1 0 -1.085 -1.040 1.180 -3.133 -2.265

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for AZGP1:


Pubmed-AZGP1 »
Uniprot-AZGP1 »
Biogrid-AZGP1 »
ProteomicsDB-AZGP1 »

Tumorportal-AZGP1 »
COSMIC-AZGP1 »
GenomeRNAi-AZGP1 »
Genecards-AZGP1


Protein-protein Interactions for AZGP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX31 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFEMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AZGP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members MHC_I/II-like_Ag-recog IPR011162 0.02
Category members MHC_I_a_a1/a2 IPR001039 0
Category members Ig_C1-set IPR003597 0
Category members MHC_I_a IPR027648 0


Protein complexes (CORUM database) featuring AZGP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AZGP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Database 2.5
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0003823 antigen binding Database 0.13
Category members GO Category GO:0008320 protein transmembrane transporter activity Database 0.06
Category members GO Category GO:0019882 antigen processing and presentation Database 0.03
Category members GO Category GO:0001916 positive regulation of T cell mediated cytotoxicity Database 0
Category members GO Category GO:0004540 ribonuclease activity Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0042605 peptide antigen binding Database 0
Category members GO Category GO:0042612 MHC class I protein complex Database 0


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