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Query: ATXN2L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATXN2L 1 3.087 -0.290 0.580 -0.053 -0.841 -0.603

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATXN2L Phosphorylation S589 0.433 0.975 _EKEVDGLLTS(ph)EPM(ox)GSPVSSK_
ATXN2L Phosphorylation S111 0.569 0.606 _GPPQS(ph)PVFEGVYNNSR_
ATXN2L Phosphorylation S594 0.171 0.492 _EVDGLLTSEPMGS(ph)PVSSK_
ATXN2L Phosphorylation S449 -0.031 0.247 _M(ox)YPPRS(ph)PK_
ATXN2L Phosphorylation S335 -0.517 0.205 _QGS(ph)GRESPSLASR_
ATXN2L Phosphorylation S339 -0.322 0.154 _QGSGRES(ph)PSLASR_
ATXN2L Phosphorylation S559 -0.284 -0.125 _LQPSSS(ph)PENSLDPFPPR_
ATXN2L Phosphorylation S306 2.721 -0.478 _EIESS(ph)PQYR_
ATXN2L Phosphorylation S680 0.025 -0.810 _STS(ph)TPTSPGPR_
ATXN2L Phosphorylation S391 -0.879 _GPHHLDNSS(ph)PGPGSEAR_
ATXN2L Phosphorylation T683 -1.044 -0.897 _STSTPT(ph)SPGPR_
ATXN2L Phosphorylation S424 -1.181 _TLSS(ph)PSNRPSGETSVPPPPAVGR_
ATXN2L Phosphorylation T421 -1.623 -1.486 _T(ph)LSSPSNRPSGETSVPPPPAVGR_
ATXN2L Phosphorylation S630 -2.209 _TESVSDKEDKPPLAPSGGTEGPEQPPPPCPS(ph)QTGSPPVGLIK_
ATXN2L Phosphorylation T632 -3.399 -2.759 _TESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT(ph)GSPPVGLIK_
ATXN2L Ubiquitylation K348 0.308 _EGK(gl)YIPLPQR_
ATXN2L Phosphorylation S423 -1.658 _TLS(ph)SPSNRPSGETSVPPPPAVGR_
ATXN2L Ubiquitylation K507 -0.776 _ISLAPTDVK(gl)ELSTKEPGR_
ATXN2L Ubiquitylation K538 -1.286 _VPGLQNEQK(gl)R_

Background Information for ATXN2L:


Pubmed-ATXN2L »
Uniprot-ATXN2L »
Biogrid-ATXN2L »
ProteomicsDB-ATXN2L »

Tumorportal-ATXN2L »
COSMIC-ATXN2L »
GenomeRNAi-ATXN2L »
Genecards-ATXN2L


Protein-protein Interactions for ATXN2L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRPF3 Cat. description Hein, Mann, Cell 2015
Category members IP bait STK17B Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEAL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATXN2L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ataxin-2_C IPR009818 0.19
Category members LsmAD_domain IPR009604 0
Category members LSM_dom IPR010920 0


Protein complexes (CORUM database) featuring ATXN2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATXN2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0034063 stress granule assembly Database 0.13
Category members GO Category GO:0003674 molecular_function Database 0.08


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