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Query: ATXN10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATXN10 0 -1.579 -0.150 -0.020 -0.206 -0.508 -0.431

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATXN10 Ubiquitylation K34 0.126 1.026 _ALTALFK(gl)EQR_
ATXN10 Ubiquitylation K56 0.941 _VLDILKK(gl)_
ATXN10 Ubiquitylation K452 0.182 -0.352 _K(gl)VGFEVEK_
ATXN10 Ubiquitylation K262 -1.225 -0.580 _ITSDEPLTK(gl)DDIPVFLR_
ATXN10 Phosphorylation S12 -1.092 -0.955 _LS(ph)GVM(ox)VPAPIQDLEALR_
ATXN10 Ubiquitylation K55 -0.127 _VLDILK(gl)K_
ATXN10 Ubiquitylation K288 -1.585 _TVLK(gl)LASEEPPDDEEALATIR_
ATXN10 Ubiquitylation K467 0.607 _LILK(gl)STR_

Background Information for ATXN10:





Protein-protein Interactions for ATXN10

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GET4 Cat. description Hein, Mann, Cell 2015
Category members IP bait LAMB3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2A Cat. description Hein, Mann, Cell 2015


Protein Domains in ATXN10

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring ATXN10

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATXN10

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0008219 cell death Database 0.08
Category members Disease phenotype Joubert_syndrome_with_renal_defect Joubert syndrome with renal defect Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0


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